CarO, anAcinetobacter baumanniiouter membrane protein involved in carbapenem resistance, is essential forl-ornithine uptake

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Channel formation by CarO, the carbapenem resistance-associated outer membrane protein of Acinetobacter baumannii.

It has been recently shown that resistance to both imipenem and meropenem in multidrug-resistant clinical strains of Acinetobacter baumannii is associated with the loss of a heat-modifiable 25/29-kDa outer membrane protein, called CarO. This study aimed to investigate the channel-forming properties of CarO. Mass spectrometry analyses of this protein band detected another 25-kDa protein (called ...

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ژورنال

عنوان ژورنال: FEBS Letters

سال: 2007

ISSN: 0014-5793

DOI: 10.1016/j.febslet.2007.10.063